Innovation is Our DNA

NGS-Verified, Cell-Free DNA Synthesis Delivers Industry-Leading Speed, Length, and Quality

ENFINIA DNA – Long, Complex, Accurate, Linear DNA Synthesis

NGS-verified, cell-free DNA synthesis
Linear DNA from 1 to 7 kb
Error rates as low as 1:70,000 bp (99.999% per base accuracy)
Shipped in 6 to 8 business days
Manufactured in the USA, shipped globally

ENFINIA - Long Linear DNA

NGS-Verified, Cell-Free DNA Synthesis for Industry-Leading Speed, Quality, and Length

We use our innovative cell-free DNA synthesis technology to rapidly produce long, complex, linear DNA without compromising accuracy or quality. Use ENFINIA DNA directly in your synthetic biology workflows with minimal or no cloning and save weeks or months of time.

Skip cloning and streamline your workflows

NGS-verified, linear DNA up to 7,000 bp shipped in 6 to 8 business days

Error rates as low as 1:70,000 bp (99.999% per base accuracy)

Now Available: High Complexity Sequences

Elegen announces expanded sequence acceptance criteria for high-complexity ENFINIA DNA

ENFINIA™ DNA with enhanced high-complexity, cell-free DNA synthesis provides rapid and reliable access to the most challenging sequences, including long repeats and STRs, GC-rich promoters, enhancers, terminators, ITRs, LTRs, and homopolymers. Delivered NGS-verified in as fast as 10 business days.

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Featured Video

Introducing ENFINIA DNA: Rapid, Cell-Free, Long, Complex, NGS-verified DNA Synthesis

Produced from Elegen's proprietary cell-free DNA production technology, ENFINIA DNA provides unprecedented speed, length, and quality. Shipped in 6 to 8 business days and up to 7 kb in length, ENFINIA DNA arrives NGS-verified with a 99.999% per base accuracy or 1:70,000 bp error rate, ready for immediate use without cloning. Unlock your synthetic biology workflows and save weeks to months on top of the personnel and equipment costs required for cell-based cloning.

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Featured News

Elegen Raises $35 Million in Series B to Accelerate Expansion into Clinical Manufacturing

Elegen announced a Series B financing of $35 million led by Triatomic Capital. Also joining the round are strategic investors GSK, which recently entered a collaboration and licensing agreement with Elegen to use their proprietary cell-free DNA manufacturing technology in developing GSK’s vaccines and medicines; John Ballantyne, co-founder of Aldevron; and existing investors.

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Innovation to Advance the Bioeconomy

Infectious Disease

As genetic medicine developers race to evolve mRNA vaccine programs for the next outbreak, rapid access to accurate, long DNA will be key to solving the critical bottleneck in DNA supply. ENFINIA DNA offers a reliable supply of high-accuracy, full-length gene synthesis. Manufactured cell free, NGS verified, and at scale, ENFINIA does not require further purification through cloning and can be immediately used for mRNA synthesis by in vitro transcription, displacing traditional master cell bank (MCB) workflows to save months of time and costs.

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Cell and Gene Therapy

Rapid access to high-accuracy, long DNA for gene synthesis can help make your gene therapy platform scalable, robust, productive, and simple. By delivering highly accurate linear DNA at lengths up to 7 kb in 6 to 8 business days, cell and gene therapy programs can save 2 to 3 weeks with every order, and over 3 months with every project, by skipping early rounds of cloning and directly assembling custom expression cassettes into plasmids for downstream cell expansion.

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Food and Agriculture

To identify and study genes and pathways linked to desirable traits important in combating exponentially growing challenges in food security and sustainability, scientists use synthetic biology tools to build highly accurate de novo assemblies or complex synthetic gene circuits that can reach over 40 kb in size. Rapid access to high-accuracy, long DNA at lengths up to 7 kb can eliminate early rounds of gene synthesis and assembly, eliminating as many as 10 weeks of assembly and cloning effort.

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Biomanufacturing

The combination of synthetic biology and evolving cell-free technologies has shown promise as a core technology for just-in-time manufacturing of valuable small molecules, therapeutically relevant biologics, antibodies, cytokines, and more. Reliable access to highly accurate, longer synthetic DNA building blocks can streamline the construction of multi-part, programmable molecular circuits by removing early assembly and cloning steps – saving weeks of development.

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Our Vision

The growing bioeconomy demands synthetic biology performs on a scale not possible without innovation of the DNA manufacturing process. Elegen will help the builders in the next evolution of synthetic biology eliminate expensive, time and capital-intensive workflows by using innovative methods and technologies to provide fast-turnaround, high-accuracy, complex, long, synthetic DNA.

Matthew Hill, Founder and CEO of Elegen

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