Next Generation Cell-Free DNA Synthesis: The DNA Buyer's Guide

Compare more than 10 leading gene synthesis vendors

Struggling to make sense of the strategies, technology and trade-offs when developing a DNA synthesis supply chain? We’ve created a comprehensive overview of the rapidly evolving field of gene synthesis as a resource for researchers looking to make informed decisions about their DNA acquisition strategies. This guide contains a detailed comparison of more than 10 industry-leading gene synthesis vendors, including key performance metrics such as error rate, turnaround time, synthesis cost, and maximum DNA length.

Topics Covered include:

  • Historical perspective on gene synthesis and the evolution of the field from early DNA discoveries to the latest advancements in next generation synthesis
  • The limitations of traditional cell-based cloning methods, such as the lengthy and error-prone process of assembling and cloning short DNA fragments.
  • Analysis of the trade-offs between in-house DNA construction and outsourcing, in terms of speed, cost, and quality for various applications.
  • Benefits of cell-free gene synthesis for various research applications, particularly those involving complex DNA constructs in IVT-mediated mRNA synthesis and AAV delivery systems for genetic medicines.

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