This whitepaper compares ENFINIA™ IVT Ready DNA, a cell-free DNA synthesis platform, against conventional plasmid-based templates for producing messenger RNA (mRNA). The study demonstrates that the ENFINIA platform overcomes key limitations of plasmids, such as long production times and poly(A) tail instability.
Key findings show that ENFINIA™ templates were synthesized significantly faster—in a consistent 12 business days versus 15 to 52 days for plasmids. The cell-free DNA also exhibited superior quality, particularly in the consistency of poly(A) tail length.
Download to learn how ENFINIA IVT Ready DNA is a high-quality, fast, and reliable alternative to plasmids for accelerating mRNA therapeutic development.