No Cloning
No Foundry
NGS-verified, cell-free DNA synthesis
Linear DNA from 1 to 7 kb with error rates as low as 1:70,000 bp (99.999% per base accuracy)
Manufactured in the USA, shipped globally
FEATURED VIDEO
Produced from Elegen’s proprietary cell-free DNA production technology, ENFINIA DNA provides unprecedented speed, length, and quality. Shipped in 6 to 8 business days and up to 7 kb in length, ENFINIA DNA arrives NGS-verified with a 99.999% per base accuracy or 1:70,000 bp error rate, ready for immediate use without cloning. Unlock your synthetic biology workflows and save weeks to months on top of the personnel and equipment costs required for cell-based cloning.
Built on Elegen’s proprietary cell-free technology, ENFINIA IVT Ready DNA delivers both standard and very complex double-stranded linear templates up to 5.5 kb that additionally include encoded poly(A) tails of 70–130 adenosines, with turnaround in as few as 10 business days. Compared to plasmid DNA, the process achieves low tail polydispersity and avoids the common pitfalls of plasmid-derived templates—including genomic DNA contamination, endotoxins from bacteria and time-consuming cloning, linearization and purification steps.
As genetic medicine developers race to evolve mRNA vaccine programs for the next outbreak, rapid access to accurate, long DNA will be key to solving the critical bottleneck in DNA supply. ENFINIA DNA offers a reliable supply of high-accuracy, full-length gene synthesis. Manufactured cell free, NGS verified, and at scale, ENFINIA does not require further purification through cloning and can be immediately used for mRNA synthesis by in vitro transcription, displacing traditional master cell bank (MCB) workflows to save months of time and costs.
Rapid access to high-accuracy, long DNA for gene synthesis can help make your gene therapy platform scalable, robust, productive, and simple. By delivering highly accurate linear DNA at lengths up to 7 kb in 6 to 8 business days, cell and gene therapy programs can save 2 to 3 weeks with every order, and over 3 months with every project, by skipping early rounds of cloning and directly assembling custom expression cassettes into plasmids for downstream cell expansion.
To identify and study genes and pathways linked to desirable traits important in combating exponentially growing challenges in food security and sustainability, scientists use synthetic biology tools to build highly accurate de novo assemblies or complex synthetic gene circuits that can reach over 40 kb in size. Rapid access to high-accuracy, long DNA at lengths up to 7 kb can eliminate early rounds of gene synthesis and assembly, eliminating as many as 10 weeks of assembly and cloning effort.
The combination of synthetic biology and evolving cell-free technologies has shown promise as a core technology for just-in-time manufacturing of valuable small molecules, therapeutically relevant biologics, antibodies, cytokines, and more. Reliable access to highly accurate, longer synthetic DNA building blocks can streamline the construction of multi-part, programmable molecular circuits by removing early assembly and cloning steps – saving weeks of development.
As genetic medicine developers race to evolve mRNA vaccine programs for the next outbreak, rapid access to accurate, long DNA will be key to solving the critical bottleneck in DNA supply. ENFINIA DNA offers a reliable supply of high-accuracy, full-length gene synthesis. Manufactured cell free, NGS verified, and at scale, ENFINIA does not require further purification through cloning and can be immediately used for mRNA synthesis by in vitro transcription, displacing traditional master cell bank (MCB) workflows to save months of time and costs.
Rapid access to high-accuracy, long DNA for gene synthesis can help make your gene therapy platform scalable, robust, productive, and simple. By delivering highly accurate linear DNA at lengths up to 7 kb in 6 to 8 business days, cell and gene therapy programs can save 2 to 3 weeks with every order, and over 3 months with every project, by skipping early rounds of cloning and directly assembling custom expression cassettes into plasmids for downstream cell expansion.
To identify and study genes and pathways linked to desirable traits important in combating exponentially growing challenges in food security and sustainability, scientists use synthetic biology tools to build highly accurate de novo assemblies or complex synthetic gene circuits that can reach over 40 kb in size. Rapid access to high-accuracy, long DNA at lengths up to 7 kb can eliminate early rounds of gene synthesis and assembly, eliminating as many as 10 weeks of assembly and cloning effort.
The combination of synthetic biology and evolving cell-free technologies has shown promise as a core technology for just-in-time manufacturing of valuable small molecules, therapeutically relevant biologics, antibodies, cytokines, and more. Reliable access to highly accurate, longer synthetic DNA building blocks can streamline the construction of multi-part, programmable molecular circuits by removing early assembly and cloning steps – saving weeks of development.
“The growing bioeconomy demands synthetic biology performs on a scale not possible without innovation of the DNA manufacturing process. Elegen will help the builders in the next evolution of synthetic biology eliminate expensive, time and capital-intensive workflows by using innovative methods and technologies to provide fast-turnaround, high-accuracy, complex, long, synthetic DNA.”
Matthew Hill
Founder and CEO of Elegen
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